On Friday 14 September, 2012, the RIPE NCC, the Regional Internet Registry (RIR) for Europe, the Middle East and parts of Central Asia, distributed the last blocks of IPv4 address space from the available pool.
This is the beginning of a whole new era. We will now start to see IPv6-only networks and some kind of NAT, allowing IPv6 networks to reach IPv4 services.
It is now imperative that all stakeholders deploy IPv6 on their networks to ensure the continuity of their online operations and the future growth of the Internet.
At this point I have to give Kuddos to services like Google which are completely IPv6-only reachable. This can not be said for Twitter and Skype, which are still lacking IPv6 connectivity and are thus lagging.